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Tenova Pharmaceuticals  |  SKU: T55033-5mg

CC-90009

$90.00
Size

Eragidomide (CC-90009) is a cereblon (CRBN) E3 ligase modulator. It acts as a molecular glue for selective degradation of GSPT1.

Product Name CC-90009
Synonyms Eragidomide
CAS Number 1860875-51-9
Related CAS
Molecular Formula C22H18ClF2N3O4
Molecular Weight 461.85
SMILES FC(F)(C(=O)NCC1=CC2=C(C=C1)C(=O)N(C2)C1CCC(=O)NC1=O)C1=CC=C(Cl)C=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Mullard, A., Targeted protein degraders crowd into the clinic. Nat Rev Drug Discov 2021, 20, 247-250.Matyskiela, M. E., Lu, G., Ito, T., Pagarigan, B., Lu, C.-C., Miller, K., Fang, W., Wang, N.-Y., Nguyen, D., Houston, J., Carmel, G., Tran, T., Riley, M., Nosaka, L. A., Lander, G. C., Gaidarova, S., Xu, S., Ruchelman, A. L., Handa, H., Carmichael, J., Daniel, T. O., Cathers, B. E., Lopez-Girona, A.,Chamberlain, P. P., A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature 2016, 535, 252-257.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

CC-90009

$90.00

Eragidomide (CC-90009) is a cereblon (CRBN) E3 ligase modulator. It acts as a molecular glue for selective degradation of GSPT1.

Product Name CC-90009
Synonyms Eragidomide
CAS Number 1860875-51-9
Related CAS
Molecular Formula C22H18ClF2N3O4
Molecular Weight 461.85
SMILES FC(F)(C(=O)NCC1=CC2=C(C=C1)C(=O)N(C2)C1CCC(=O)NC1=O)C1=CC=C(Cl)C=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Mullard, A., Targeted protein degraders crowd into the clinic. Nat Rev Drug Discov 2021, 20, 247-250.Matyskiela, M. E., Lu, G., Ito, T., Pagarigan, B., Lu, C.-C., Miller, K., Fang, W., Wang, N.-Y., Nguyen, D., Houston, J., Carmel, G., Tran, T., Riley, M., Nosaka, L. A., Lander, G. C., Gaidarova, S., Xu, S., Ruchelman, A. L., Handa, H., Carmichael, J., Daniel, T. O., Cathers, B. E., Lopez-Girona, A.,Chamberlain, P. P., A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature 2016, 535, 252-257.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
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