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CC0651 is an E2 enzyme inhibitor. It stabilizes the noncovalent CDC34A-donor ubiquitin complex . Reference: Huang, H., Ceccarelli, D. F., Orlicky, S., St-Cyr, D. J., Ziemba, A., Garg, P., Plamondon, S., Auer, M., Sidhu, S., Marinier, A., Kleiger, G., Tyers, M., & Sicheri, F. (2014). E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nature Chemical Biology, 10(2), 156–163.
Product Name CC0651
CAS Number 1319207-44-7
Related CAS
Molecular Formula C21H23Cl2NO5
Molecular Weight 440.32
SMILES COCC(=O)N[C@@H](CC1=CC=C(C=C1)C1=CC(Cl)=CC(Cl)=C1)[C@H](O)[C@@H](O)C(C)=O
Purity (HPLC) 98%
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Regulatory Statemen: For Research Use Only