CDr17 (M1 macrophage live cell dye)



Size: 1mg

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CDr17 is a selective small-molecule fluorescent probe for M1 macrophages. The molecular target of CDr17 is GLUT1. GLUT1 was validated to be highly expressed in M1 than M0 and M2 macrophages, and CDr17 utilizes GLUT1 to enter M1 macrophages. CDr17 has been demonstrated to track M1 macrophages in vivo in a rheumatoid arthritis animal model. Excitation maximum = 649 nm; emission maximum = 672 nm.

Product Name CDr17
CAS Number N/A
Related CAS
Molecular Formula C39H52IN3O6
Molecular Weight 785.764
Purity (HPLC) >= 95%
Physical Appearance Dark blue solid
Optical Properties Abs/Em Maxima: 649/672 nm
Solubility DMSO
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


Cho, H., Kwon, H. Y., Sharma, A., Lee, S. H., Liu, X., Miyamoto, N., Kim, J. J., Im, S. H., Kang, N. Y., & Chang, Y. T. (2022). Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target. Nature Communications, 13(1).


Datasheet        MSDS


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