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Tenova Pharmaceuticals  |  SKU: T55029-10mg

compound I-9

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Compound I-9 induces degradation of GSPT1 through recruitment of CRBN ( EC50: 0.170 uM).

Product Name compound I-9
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C27H29N5O3
Molecular Weight 471.561
SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)N1CCC(=CC1)C1=CC2=NC=C(N2C=C1)N1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Axford, J., Beckwith, R. E. J., BONAZZI, S., Buschmann, N., CERNIJENKO, A., DEWHURST, J., FAZAL, A., HESSE, M. J., HOLDER, L., HORNAK, V., Imase, H., Jain, R., Jin, X., Kerrigan, J. R., Lachal, J., Ma, F., Malik, H. A., MANNING, J. R., Mckay, D., MOREAU, R. J., NIMSGERN, P., O'Brien, G., Vulpetti, A., Yamada, K.,Zhao, J. Glue degraders and methods of use thereof. WO 2021/053555, 2021.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

compound I-9

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Compound I-9 induces degradation of GSPT1 through recruitment of CRBN ( EC50: 0.170 uM).

Product Name compound I-9
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C27H29N5O3
Molecular Weight 471.561
SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)N1CCC(=CC1)C1=CC2=NC=C(N2C=C1)N1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Axford, J., Beckwith, R. E. J., BONAZZI, S., Buschmann, N., CERNIJENKO, A., DEWHURST, J., FAZAL, A., HESSE, M. J., HOLDER, L., HORNAK, V., Imase, H., Jain, R., Jin, X., Kerrigan, J. R., Lachal, J., Ma, F., Malik, H. A., MANNING, J. R., Mckay, D., MOREAU, R. J., NIMSGERN, P., O'Brien, G., Vulpetti, A., Yamada, K.,Zhao, J. Glue degraders and methods of use thereof. WO 2021/053555, 2021.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
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