HaloTag DOTA-tris(t-Bu) Ligand

$290.00

T01227-1mg

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HaloTag is a self-labeling protein derived from the haloalkane dehalogenase DhaA from Rhodococcus rhodochrous. Its active site reacts with chloroalkane substrates to form an irreversible bond. The covalent linkage between the HaloTag ligand and HaloTag protein enables rapid isolation and purification. HaloTag DOTA-tris(t-Bu) Ligand can be used to attach DOTA moiety to protein. DOTA has been used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents.

Product Name HaloTag DOTA-tris(t-Bu) Ligand
Synonyms
CAS Number 1334953-45-5 
Related CAS
Molecular Formula C38H72ClN5O9
Molecular Weight 778.47
Purity (HPLC) >= 95%
Physical Appearance Light Yellow Solid
Optical Properties n/a
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Wilhelm, J., Kuhn, S., Tarnawski, M., Gotthard, G., Tunnermann, J., Tanzer, T., Karpenko, J., Mertes, N., Xue, L., Uhrig, U., Reinstein, J., Hiblot, J., & Johnsson, K. (2021). Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60(33), 2560–2575. https://doi.org/10.1021/acs.biochem.1c00261

 

Documents 

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Citations

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