HB007
HB007 - 5mg is backordered and will ship as soon as it is back in stock.
Couldn't load pickup availability
HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers.
| Product Name | HB007 |
| Synonyms | |
| CAS Number | 2387821-46-5 |
| Related CAS | |
| Molecular Formula | C15H9ClN4S2 |
| Molecular Weight | 344.84 |
| SMILES | ClC1=CC(NC(=S)NC2=NC3=C(S2)C=C(C=C3)C#N)=CC=C1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Bellail, A. C., Jin, H. R., Lo, H. Y., Jung, S. H., Hamdouchi, C., Kim, D., Higgins, R. K., Blanck, M., le Sage, C., Cross, B. C. S., Li, J., Mosley, A. L., Wijeratne, A. B., Jiang, W., Ghosh, M., Zhao, Y. Q., Hauck, P. M., Shekhar, A.,Hao, C., Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med 2021, 13, eabh1486.
Documents
Datasheet COA MSDS
Citations
If you know of a paper that uses this product from Tenova Pharma, please let us know.
