5-10 business days

HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers. Reference: Bellail, A. C., Jin, H. R., Lo, H. Y., Jung, S. H., Hamdouchi, C., Kim, D., Higgins, R. K., Blanck, M., le Sage, C., Cross, B. C. S., Li, J., Mosley, A. L., Wijeratne, A. B., Jiang, W., Ghosh, M., Zhao, Y. Q., Hauck, P. M., Shekhar, A.,Hao, C., Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med 2021, 13, eabh1486.
Product Name HB007
CAS Number 2387821-46-5
Related CAS
Molecular Formula C15H9ClN4S2
Molecular Weight 344.84
Purity (HPLC) 98%
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Regulatory Statemen: For Research Use Only