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HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers.

Product Name HB007
CAS Number 2387821-46-5
Related CAS
Molecular Formula C15H9ClN4S2
Molecular Weight 344.84
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


Bellail, A. C., Jin, H. R., Lo, H. Y., Jung, S. H., Hamdouchi, C., Kim, D., Higgins, R. K., Blanck, M., le Sage, C., Cross, B. C. S., Li, J., Mosley, A. L., Wijeratne, A. B., Jiang, W., Ghosh, M., Zhao, Y. Q., Hauck, P. M., Shekhar, A.,Hao, C., Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med 2021, 13, eabh1486.



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