MaP555 Acid (cell-permeable fluorogenic dye)

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T01218-5mg

Size: 5mg

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MaP555 is a small-molecule fluorogenic probe with excellent cell permeability. It is converted from 6-carboxytetramethylrhodamine (6-TAMRA) and has similar spectroscopic properties of 6-TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good spectroscopic properties, high cell permeability and outstanding fluorogenicity of MaP555 make it very useful for wash-free, multicolour, live-cell nanoscopy. Excitation maximum = 553 nm; emission maximum = 580 nm.

Product Name MaP555 Acid
Synonyms
CAS Number 2434651-26-8
Related CAS
Molecular Formula C27H28N4O6S
Molecular Weight 536.6
Purity (HPLC) >= 95%
Physical Appearance Red solid
Optical Properties Abs/Em Maxima: 553/580 nm
Solubility DMSO
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Wang, L., Tran, M., D’Este, E., Roberti, J., Koch, B., Xue, L., & Johnsson, K. (2020). A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy. Nature Chemistry, 12(2), 165–172. https://doi.org/10.1038/s41557-019-0371-1


Documents 

Datasheet         COA           MSDS


Citations

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