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Tenova Pharmaceuticals  |  SKU: T55049-10mg

NCT 02

$190.00
Size

NCT02 is a molecular glue cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12.

Product Name NCT 02
Synonyms
CAS Number 790245-61-3
Related CAS
Molecular Formula C17H16N2O2S
Molecular Weight 312.39
SMILES CC1=CN=C(NC(=O)CC2=COC3=CC4=C(CCC4)C=C23)S1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Dieter, S. M., Siegl, C., Codo, P. L., Huerta, M., Ostermann-Parucha, A. L., Schulz, E., Zowada, M. K., Martin, S., Laaber, K., Nowrouzi, A., Blatter, M., Kreth, S., Westermann, F., Benner, A., Uhrig, U., Putzker, K., Lewis, J., Haegebarth, A., Mumberg, D., Holton, S. J., Weiske, J., Toepper, L.-M., Scheib, U., Siemeister, G., Ball, C. R., Kuster, B., Stoehr, G., Hahne, H., Johannes, S., Lange, M., Herbst, F.,Glimm, H., Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer. Cell Reports 2021, 36.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

NCT 02

$190.00

NCT02 is a molecular glue cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12.

Product Name NCT 02
Synonyms
CAS Number 790245-61-3
Related CAS
Molecular Formula C17H16N2O2S
Molecular Weight 312.39
SMILES CC1=CN=C(NC(=O)CC2=COC3=CC4=C(CCC4)C=C23)S1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Dieter, S. M., Siegl, C., Codo, P. L., Huerta, M., Ostermann-Parucha, A. L., Schulz, E., Zowada, M. K., Martin, S., Laaber, K., Nowrouzi, A., Blatter, M., Kreth, S., Westermann, F., Benner, A., Uhrig, U., Putzker, K., Lewis, J., Haegebarth, A., Mumberg, D., Holton, S. J., Weiske, J., Toepper, L.-M., Scheib, U., Siemeister, G., Ball, C. R., Kuster, B., Stoehr, G., Hahne, H., Johannes, S., Lange, M., Herbst, F.,Glimm, H., Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer. Cell Reports 2021, 36.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
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