NDB-TM (HOCl probe)

$90.00

T01214-1mg

Size: 1mg

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NBD-TM is a thiomorpholine-based fluorogenic probe for HOCl. NBD-TM proved to be the most rapid scavenger of HOCl when compared with boronate- and aminophenyl-based fluorogenic probes in a study for monitoring the chlorinating activity of Myeloperoxidase (MPO). Its high reactivity towards HOCl makes NBD-TM the probe of choice for HTS campaigns based on HOCl detection. Excitation maximum = 500 nm; emission maximum = 550 nm.

Product Name NDB-TM
Synonyms
CAS Number 871510-38-2
Related CAS
Molecular Formula C10H10N4O3S
Molecular Weight 266.28
Purity (HPLC) >= 95%
Physical Appearance Brown Solid
Optical Properties Abs/Em Maxima: 500/550nm
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Pierzchala, K., Pieta, M., Rola, M., Swierczynska, M., Artelska, A., Debowska, K., Podsiadly, R., Pieta, J., Zielonka, J., Sikora, A., Marcinek, A., & Michalski, R. (2022). Fluorescent probes for monitoring myeloperoxidase-derived hypochlorous acid: a comparative study. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-13317-8


Documents 

Datasheet         COA           MSDS


Citations

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