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Tenova Pharmaceuticals  |  SKU: T55011-1mg

NRX-1532

$190.00
Size

NRX-1532 is an enhancer of the interaction between beta-catenin and beta-TrCP. NRX-1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome.

Product Name NRX-1532
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C16H11F3N4O2
Molecular Weight 348.285
SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=CC=NN2)C(=O)N1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Simonetta, K. R., Taygerly, J., Boyle, K., Basham, S. E., Padovani, C., Lou, Y., Cummins, T. J., Yung, S. L., von Soly, S. K., Kayser, F., Kuriyan, J., Rape, M., Cardozo, M., Gallop, M. A., Bence, N. F., Barsanti, P. A.,Saha, A., Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 2019, 10, 1402.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

NRX-1532

From $190.00

NRX-1532 is an enhancer of the interaction between beta-catenin and beta-TrCP. NRX-1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome.

Product Name NRX-1532
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C16H11F3N4O2
Molecular Weight 348.285
SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=CC=NN2)C(=O)N1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Simonetta, K. R., Taygerly, J., Boyle, K., Basham, S. E., Padovani, C., Lou, Y., Cummins, T. J., Yung, S. L., von Soly, S. K., Kayser, F., Kuriyan, J., Rape, M., Cardozo, M., Gallop, M. A., Bence, N. F., Barsanti, P. A.,Saha, A., Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 2019, 10, 1402.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

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