Pomalidomide-acetamido-O-PEG2-C2-azide

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T52110-100mg

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Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal azide. Ready for conjugation to a target protein ligand through click reaction to form PROTACs containing Pomalidomide as cereblon ligand.

Product Name: Pomalidomide-acetamido-O-PEG2-C2-azide
Synonyms: Acetamide, 2-?[2-?[2-?(2-?azidoethoxy)?ethoxy]?ethoxy]?-?N-?[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?-
CAS Number:  2267306-15-8
Molecular Formula: C21H24N6O8
Molecular Weight: 488.457
SMILES: [N-]=[N+]=NCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only