Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal alkyne. Ready for conjugation to a target protein ligand through click reaction to form PROTACs containing Pomalidomide as cereblon ligand.
Product Name: | Pomalidomide-CO-PEG3-propargyl |
Synonyms: | Propanamide, N-?[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?-?3-?[2-?[2-?(2-?propyn-?1-?yloxy)?ethoxy]?ethoxy]?- |
CAS Number: | 2236109-20-7 |
Molecular Formula: | C23H25N3O8 |
Molecular Weight: | 471.466 |
SMILES: | O=C(CCOCCOCCOCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |