Pomalidomide-CO-PEG3-propargyl

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T52072-100mg

Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal alkyne. Ready for conjugation to a target protein ligand through click reaction to form PROTACs containing Pomalidomide as cereblon ligand.

Product Name: Pomalidomide-CO-PEG3-propargyl
Synonyms: Propanamide, N-?[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?-?3-?[2-?[2-?(2-?propyn-?1-?yloxy)?ethoxy]?ethoxy]?-
CAS Number: 2236109-20-7
Molecular Formula: C23H25N3O8
Molecular Weight: 471.466
SMILES: O=C(CCOCCOCCOCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only