Pyrrolidone1 selectively stabilizes the 14–3–3/PMA2 protein–protein interaction.
| Product Name | Pyrrolidone 1 |
| Synonyms | |
| CAS Number | 296797-88-1 |
| Related CAS | |
| Molecular Formula | C25H18N2O7 |
| Molecular Weight | 458.426 |
| SMILES | CC1=C(C(N(C1=O)C1=CC(C(O)=O)=C(O)C=C1)C1=CC=C(C=C1)[N+]([O-])=O)C(=O)C1=CC=CC=C1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Rose, R., Erdmann, S., Bovens, S., Wolf, A., Rose, M., Hennig, S., Waldmann, H.,Ottmann, C., Identification and Structure of Small-Molecule Stabilizers of 14–3–3 Protein–Protein Interactions. Angewandte Chemie International Edition 2010, 49, 4129-4132. DOI: 10.1002/anie.200907203
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Citations
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