(S,R,S)-AHPC-acetamido-O-PEG2-C1-acid

T53070-10mg

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Proteolysis targeting chimera (PROTAC) building block. Contains (S,R,S)-AHPC as von Hippel-Lindau (VHL) ligand with PEG linker and a terminal caboxylic acid moiety. Ready for conjugation to a target protein ligand to form PROTACs containing (S,R,S)-AHPC as E3 ligase ligand.

Product Name: (S,R,S)-AHPC-acetamido-O-PEG2-C1-acid
Synonyms: L-?Prolinamide, N-?[2-?[2-?[2-?(carboxymethoxy)?ethoxy]?ethoxy]?acetyl]?-?3-?methyl-?L-?valyl-?4-?hydroxy-?N-?[[4-?(4-?methyl-?5-?thiazolyl)?phenyl]?methyl]?-?, (4R)?-
CAS Number: 2172820-10-7
Molecular Formula: C30H42N4O9S
Molecular Weight: 634.75
SMILES: CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC(O)=O)C(C)(C)C)C=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only