SKU: T53059-25mg

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Proteolysis targeting chimera (PROTAC) building block. Contains (S,R,S)-AHPC as von Hippel-Lindau (VHL) ligand with alkyl linker and a terminal caboxylic acid moiety. Ready for conjugation to a target protein ligand to form PROTACs containing (S,R,S)-AHPC as E3 ligase ligand.

Product Name: (S,R,S)-AHPC-CO-C2-acid
Synonyms: 4-?(((S)?-?1-?((2S,?4R)?-?4-?Hydroxy-?2-?((4-?(4-?methylthiazol-?5-?yl)?benzyl)?carbamoyl)?pyrrolidin-?1-?yl)?-?3,?3-?dimethyl-?1-?oxobutan-?2-?yl)?amino)?-?4-?oxobutanoic acid
CAS Number:  2172819-72-4
Molecular Formula: C26H34N4O6S
Molecular Weight: 530.64
SMILES: CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCC(O)=O)C(C)(C)C)C=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only