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SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. SNAP-tag reacts with covalently with O6-benzylguanine derivatives. SNAP-DBCO can be used to attach DBCO moiety to protein. DBCO has been extensively used in copper-free click chemistry.

Product Name SNAP-DBCO
CAS Number 1820756-74-8 
Related CAS
Molecular Formula C32H27N7O3
Molecular Weight 557.614
Purity (HPLC) >= 95%
Physical Appearance White Solid
Optical Properties n/a
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


Wilhelm, J., Kuhn, S., Tarnawski, M., Gotthard, G., Tunnermann, J., Tanzer, T., Karpenko, J., Mertes, N., Xue, L., Uhrig, U., Reinstein, J., Hiblot, J., & Johnsson, K. (2021). Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60(33), 2560–2575.



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