Thalidomide-C3-O-PEG4-C2-acid

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T52266-100mg

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Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal carboxylic acid. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.

Product Name: Thalidomide-C3-O-PEG4-C2-acid
Synonyms: 4,?7,?10,?13,?16-?Pentaoxanonadecanoic acid, 19-?[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?-
CAS Number: 2376139-69-2
Molecular Formula: C27H36N2O11
Molecular Weight: 564.588
SMILES: OC(=O)CCOCCOCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only