Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal amine. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.
Product Name: | Thalidomide-O-acetamido-C3-amine HCl |
Synonyms: | Acetamide, N-?(3-?aminopropyl)?-?2-?[[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?oxy]?- |
CAS Number: | 2022182-57-4 |
Molecular Formula: | C18H21ClN4O6 |
Molecular Weight: | 424.84 |
SMILES: | Cl.NCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |