Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal carboxylic acid. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.
Product Name: | Thalidomide-O-acetamido-PEG1-C2-acid |
Synonyms: | Propanoic acid, 3-?[2-?[[2-?[[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?oxy]?acetyl]?amino]?ethoxy]?- |
CAS Number: | 2204225-99-8 |
Molecular Formula: | C20H21N3O9 |
Molecular Weight: | 447.4 |
SMILES: | OC(=O)CCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |