Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
Product Name: | Thalidomide-O-C2-alkyne |
Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 4-?(3-?butyn-?1-?yloxy)?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?- |
CAS Number: | 2357110-34-8 |
Molecular Formula: | C17H14N2O5 |
Molecular Weight: | 326.308 |
SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCC#C)C=CC=C12 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |