Thalidomide-O-C2-alkyne

$490.00

T52144-100mg

Ships in 5-10 Business Days

Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.

Product Name: Thalidomide-O-C2-alkyne
Synonyms: 1H-?Isoindole-?1,?3(2H)?-?dione, 4-?(3-?butyn-?1-?yloxy)?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?-
CAS Number: 2357110-34-8
Molecular Formula: C17H14N2O5
Molecular Weight: 326.308
SMILES: O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCC#C)C=CC=C12
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only