Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-O-C2-alkyne |
| Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 4-?(3-?butyn-?1-?yloxy)?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?- |
| CAS Number: | 2357110-34-8 |
| Molecular Formula: | C17H14N2O5 |
| Molecular Weight: | 326.308 |
| SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCC#C)C=CC=C12 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |