Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-O-PEG1-propargyl |
| Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 2-?(2,?6-?dioxo-?3-?piperidinyl)?-?4-?[2-?(2-?propyn-?1-?yloxy)?ethoxy]?- |
| CAS Number: | 2098487-79-5 |
| Molecular Formula: | C18H16N2O6 |
| Molecular Weight: | 356.334 |
| SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCC#C)C=CC=C12 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |