Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-O-PEG3-propargyl |
| Synonyms: | 2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethoxy]-1H-isoindole-1,3(2H)-dione |
| CAS Number: | 2098799-76-7 |
| Molecular Formula: | C22H24N2O8 |
| Molecular Weight: | 444.44 |
| SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCCOCCOCC#C)C=CC=C12 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |