Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-O-PEG4-propargyl |
| Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 2-?(2,?6-?dioxo-?3-?piperidinyl)?-?4-?(3,?6,?9,?12-?tetraoxapentadec-?14-?yn-?1-?yloxy)?- |
| CAS Number: | 2098799-77-8 |
| Molecular Formula: | C24H28N2O9 |
| Molecular Weight: | 488.493 |
| SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCCOCCOCCOCC#C)C=CC=C12 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |