Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal carboxylic acid. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.
Product Name: | Thalidomide-O-PEG5-C2-acid |
Synonyms: | Propanoic acid, 3-?[[14-?[[2-?(2,?6-?dioxo-?3-?piperidinyl)?-?2,?3-?dihydro-?1,?3-?dioxo-?1H-?isoindol-?4-?yl]?oxy]?-?3,?6,?9,?12-?tetraoxatetradec-?1-?yl]?oxy]?- |
CAS Number: | 2353563-48-9 |
Molecular Formula: | C26H34N2O12 |
Molecular Weight: | 566.56 |
SMILES: | OC(=O)CCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |