Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal alkyne. Ready for conjugation to a target protein ligand through click chemistry to form PROTACs containing Thalidomide as cereblon ligand.
Product Name: | Thalidomide-O-propargyl |
Synonyms: | 2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy]isoindoline-1,3-dione |
CAS Number: | 2098487-39-7 |
Molecular Formula: | C16H12N2O5 |
Molecular Weight: | 312.281 |
SMILES: | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCC#C)C=CC=C12 |
Purity (HPLC): | 95% |
Shipping Conditions: | room temperature |
Storage Conditions: | Refrigerated |
Regulatory Statement: | For Research Use Only |