Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with alkyl linker and terminal alcohol. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-propargyl-O-PEG1-OH |
| Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 2-?(2,?6-?dioxo-?3-?piperidinyl)?-?4-?[3-?(2-?hydroxyethoxy)?-?1-?propyn-?1-?yl]?- |
| CAS Number: | 2416133-05-4 |
| Molecular Formula: | C18H16N2O6 |
| Molecular Weight: | 356.334 |
| SMILES: | OCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |