Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal amine. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.
| Product Name: | Thalidomide-propargyl-O-PEG3-C2-amine HCl |
| Synonyms: | 1H-?Isoindole-?1,?3(2H)?-?dione, 4-?(15-?amino-?4,?7,?10,?13-?tetraoxapentadec-?1-?yn-?1-?yl)?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?- |
| CAS Number: | 2357112-93-5 |
| Molecular Formula: | C24H30ClN3O8 |
| Molecular Weight: | 523.97 |
| SMILES: | Cl.NCCOCCOCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 |
| Purity (HPLC): | 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |