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Tram-bo is the fluorescent probe used in the discovery of Trametiglue. It contains an BODIPY moeity connected to Trametiglue scaffold.

Product Name Tram-bo
CAS Number n/a
Related CAS
Molecular Formula C47H46BF3IN9O7
Molecular Weight 1043.65
Purity (HPLC) >= 95%
Physical Appearance Dark Solid
Optical Properties Abs/Em Maxima: 576/589nm
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


Khan, Z.M., Real, A.M., Marsiglia, W.M. et al. Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature 588, 509–514 (2020).



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