Order Online and Get 10% Off

Tenova Pharmaceuticals  |  SKU: T55053-5mg

V1

$0.00
Size

V1 acts as a molecular glue to stabilize the symmetrical dimer of the TrkA kinase domains. V1 binds to the ATP-binding site and simultaneously engages in the dimeric interface of TrkA.

Product Name V1
Synonyms
CAS Number 1802770-18-8
Related CAS
Molecular Formula C31H32N4O4
Molecular Weight 524.621
SMILES NC1=C2C(=O)C3=C(C=CC=C3)C(=O)C2=C(NC2=CC=C(C=C2)C(O)=O)C=C1N1CCN(CC1)C1CCCCC1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Furuya, N., Momose, T., Katsuno, K., Fushimi, N., Muranaka, H., Handa, C., Sawa, M., Ozawa, T.,Kinoshita, T., An isoform-selective inhibitor of tropomyosin receptor kinase A behaves as molecular glue. Bioorganic & Medicinal Chemistry Letters 2020, 30, 126775.https://doi.org/10.1016/j.bmcl.2019.126775

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.