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Tenova Pharmaceuticals | SKU:
T55053-5mg
V1
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V1 - 5mg is backordered and will ship as soon as it is back in stock.
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V1 acts as a molecular glue to stabilize the symmetrical dimer of the TrkA kinase domains. V1 binds to the ATP-binding site and simultaneously engages in the dimeric interface of TrkA.
| Product Name | V1 |
| Synonyms | |
| CAS Number | 1802770-18-8 |
| Related CAS | |
| Molecular Formula | C31H32N4O4 |
| Molecular Weight | 524.621 |
| SMILES | NC1=C2C(=O)C3=C(C=CC=C3)C(=O)C2=C(NC2=CC=C(C=C2)C(O)=O)C=C1N1CCN(CC1)C1CCCCC1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Furuya, N., Momose, T., Katsuno, K., Fushimi, N., Muranaka, H., Handa, C., Sawa, M., Ozawa, T.,Kinoshita, T., An isoform-selective inhibitor of tropomyosin receptor kinase A behaves as molecular glue. Bioorganic & Medicinal Chemistry Letters 2020, 30, 126775.https://doi.org/10.1016/j.bmcl.2019.126775
Documents
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Citations
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