ZXH-1-161
ZXH-1-161 - 5mg is backordered and will ship as soon as it is back in stock.
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ZXH-1-161
ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma.
| Product Name | ZXH-1-161 |
| Synonyms | |
| CAS Number | 2407654-51-5 |
| Related CAS | |
| Molecular Formula | C26H24N6O3 |
| Molecular Weight | 468.517 |
| SMILES | O=C1N(CC2=C1C=CC=C2NC1=NC(NC2=CC3=C(CCC3)C=C2)=NC=C1)C1CCC(=O)NC1=O |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Powell, C. E., Du, G., Che, J., He, Z., Donovan, K. A., Yue, H., Wang, E. S., Nowak, R. P., Zhang, T., Fischer, E. S.,Gray, N. S., Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chemical Biology 2020, 15, 2722-2730.
Documents
Datasheet COA MSDS
Citations
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